Gossypium hirsutum is a member of the Malvaceae family, native to Central America and Mexico. Gossypium hirsutum produces high-grade cotton fibers that are long and robust making it one of the most important economic crops worldwide. Additionally, it provides the world's largest source of natural fibers for the global textile industry[1]. With the in-depth study of cotton cell development process, single-cell sequencing technology provides a new method for cotton breeding. From now, it has been used to construct the developmental trajectory of cotton fiber cells at the single-cell[2] and the single-cell transcriptional maps of glandular and non-glandular in cotton cotyledons[3], and resolve cotton somatic embryogenesis mechanism at the single-cell[4].

[1] Tian Z, Zhang Y, Zhu L, et al. Strigolactones act downstream of gibberellins to regulate fiber cell elongation and cell wall thickness in cotton (Gossypium hirsutum)[J]. The Plant Cell, 2022, 34(12): 4816-4839.
[2] Qin Y, Sun M, Li W, et al. Single‐cell RNA‐seq reveals fate determination control of an individual fibre cell initiation in cotton (Gossypium hirsutum)[J]. Plant biotechnology journal, 2022, 20(12): 2372-2388.
[3] Long L, Xu F C, Wang C H, et al. Single‐cell transcriptome atlas identified novel regulators for pigment gland morphogenesis in cotton[J]. Plant Biotechnology Journal, 2023, 21(6): 1100.
[4] Zhu X, Xu Z, Wang G, et al. Single-cell resolution analysis reveals the preparation for reprogramming the fate of stem cell niche in cotton lateral meristem[J]. Genome biology, 2023, 24(1): 194.

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